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MLN4924 and Neddylation: Targeting UBE2F-SAG Axis in Tumo...
2025-09-22
Explore the mechanistic impact of the NEDD8-activating enzyme inhibitor MLN4924 on the UBE2F-SAG neddylation axis, with implications for cancer biology research and anti-cancer therapeutic development. This article provides new insights into selective NAE inhibition and its effects on tumor growth regulation.
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Cyclopamine: A Precise Hedgehog Pathway Inhibitor for Can...
2025-09-19
Explore the multifaceted roles of Cyclopamine, a potent Hedgehog signaling pathway inhibitor, in cancer research and developmental biology. This article examines its mechanism as a Smoothened receptor antagonist and discusses unique experimental considerations for its use in breast and colorectal cancer models.
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Lenalidomide hydrochloride
2025-09-19
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Gemcitabine HCl
2025-09-18
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Z-VAD-FMK: Illuminating Apoptotic Pathways Beyond Transcr...
2025-09-18
Explore the mechanistic role of Z-VAD-FMK, a cell-permeable pan-caspase inhibitor, in dissecting apoptotic signaling initiated by RNA Pol II inhibition. This article provides evidence-based insights into how Z-VAD-FMK advances apoptosis research in THP-1 and Jurkat T cells, with distinct implications for cancer and neurodegenerative disease models.
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AEF0117
2025-09-17
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NMS-1286937
2025-09-17
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Annexin V-Cy5SYTOX Green Apoptosis Kit
2025-09-16
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Anti-RPA70 Mouse Monoclonal Antibody
2025-09-16
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Afatinib (BIBW2992)
2025-09-15
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ART558
2025-09-15
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Anti-ADAM17 Rabbit Monoclonal Antibody
2025-09-13
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Tranilast Sodium
2025-09-12
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Anti-SLAMF7CS1 Antibody (AzintuxizumAb)
2025-09-12
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Boc-D-Trp(For)-OH
2025-09-11